MGC109416 antibody, NR2B3 antibody, Nuclear receptor subfamily 2 group B member 3 antibody, OTTHUMP00000060418 antibody, Retanoic X receptor gamma antibody, Retinoic acid receptor RXR gamma antibody, Retinoic acid receptor RXR-gamma antibody, Retinoid X receptor gamma antibody, RXR G antibody, RXR gamma antibody, RXRC antibody, Rxrg antibody, RXRG_HUMAN antibody, RXRgamma antibody
Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXRalpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Source:
Synthetic peptide corresponding to amino acid residues from the hinge region of human retinoid X receptor, gamma-isotype, conjugated to keyhole limpet hemocyanin (KLH).
Target:
Retinoid X Receptor, gamma-Isotype
Application Dilute:
WB(1:300-5000)
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