Thyroid Hormone Receptor, ß-Isotype Antibody, IgG1, Clone: [2386], Unconjugated, Mouse, Monoclonal

Product Overview

• Article Name: Thyroid Hormone Receptor, ß-Isotype Antibody, IgG1, Clone: [2386], Unconjugated, Mouse, Monoclonal
• Biozol Catalog Number: BSS-BSM-70288M
• Supplier Catalog Number: bsm-70288M
• Alternative Catalog Number: BSS-BSM-70288M-100
• Manufacturer: Bioss
• Host: Mouse
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: Avian erythroblastic leukemia viral (v erb a) oncogene homolog 2 antibody, C ERBA 2 antibody, C ERBA BETA antibody, c-erbA-2 antibody, c-erbA-beta antibody, ERBA 2 antibody, ERBA BETA antibody, ERBA2 antibody, Erythroblastic leukemia viral (v erb a) oncogene homolog 2 avian antibody, generalized resistance to thyroid hormone antibody, GRTH antibody, MGC126109 antibody, MGC126110 antibody, NR1A2 antibody, Nuclear receptor subfamily 1 group A member 2 antibody, Oncogene ERBA2 antibody, PRTH antibody, THB_HUMAN antibody, THR1 antibody, THRB 1 antibody, THRB 2 antibody, thrB antibody, THRB1 antibody, THRB2 antibody, Thyroid hormone nuclear receptor beta variant 1 antibody, Thyroid hormone receptor beta 1 antibody, Thyroid hormone receptor beta 2 antibody, Thyroid hormone receptor beta antibody, Thyroid hormone receptor beta (erythroblastic leukemia viral (v erb a) oncogene homolog 2 avian) antibody

Product Description

Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRalpha1, TRalpha2, TRbeta1 and TRbeta2. TRalpha1, TRbeta1 and TRbeta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).

Product Properties

• Clonality: Monoclonal
• Concentration: Lot Dependent
• Clone Designation: [2386]
• Isotype: IgG1
• NCBI: 7068
• UniProt: P10828
• Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
• Source: Synthetic peptide corresponding to amino acid residues from the N-terminal region of human thyroid hormone receptor, beta-isotype, conjugated to keyhole limpet hemocyanin (KLH).
• Target: Thyroid Hormone Receptor, ß-Isotype

Application Notes

• Application Dilute: WB(1:300-5000)