Human PARP Ready-To-Use IHC Kit

Product Overview

• Article Name: Human PARP Ready-To-Use IHC Kit
• Biozol Catalog Number: BSS-IHC0319H
• Supplier Catalog Number: IHC0319H
• Alternative Catalog Number: BSS-IHC0319H-50
• Manufacturer: Bioss
• Category: Kits/Assays
• Species Reactivity: Human
• Alternative Names: 5830444G22Rik, Adprp, ADPRT, ADPRT 1, ADPRT1, AI893648, ARTD1, C80510, pADPRT-1, PARP, PARP-1, PARP1, PPOL, sPARP-1, poly(ADP-ribose) polymerase

Product Description

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.

Product Properties

• Samples: FFPE tissue
• Target: Human PARP