GABBR2, Gb2, Gm425, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099, gamma-aminobutyric acid type B receptor subunit 2.
The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Samples:
FFPE tissue
Target:
Mouse GABBR2
IHC0385M
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