Human VEGFR2 Ready-To-Use IHC Kit

Catalog Number: BSS-IHC0459H
Article Name: Human VEGFR2 Ready-To-Use IHC Kit
Biozol Catalog Number: BSS-IHC0459H
Supplier Catalog Number: IHC0459H
Alternative Catalog Number: BSS-IHC0459H-50
Manufacturer: Bioss
Category: Kits/Assays
Species Reactivity: Human
Alternative Names: 6130401C07, Krd-1, sVEGFR-2, VEGF Receptor 2, CD309, CD309 antigen, Fetal liver kinase 1, FLK-1, FLK1, KDR, Kinase insert domain receptor (a type III receptor tyrosine kinase), Kinase insert domain receptor, KRD1, Ly73, Protein tyrosine kinase receptor FLK1, Protein-tyrosine kinase receptor flk-1, Tyrosine kinase growth factor receptor, Vascular endothelial growth factor receptor 2, VEGFR 2, VEGFR, VEGFR-2, VEGFR2, VGFR2_HUMANa
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors. FLK1 (VEGF Receptor 2) encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. The signalling and trafficking ofthis receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of FLK1 (VEGF Receptor2) are implicated in infantile capillary hemangiomas.
Samples: FFPE tissue
Target: Human VEGFR2
IHC0459H