SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma. SMAD proteins are signaltransducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thoughtto play a role in the regulation of carcinogenesis.
Samples:
FFPE tissue
Target:
Human Smad3
IHC0480H
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