Rat DARPP32 Ready-To-Use IHC Kit

Product Overview

• Article Name: Rat DARPP32 Ready-To-Use IHC Kit
• Biozol Catalog Number: BSS-IHC0670R
• Supplier Catalog Number: IHC0670R
• Alternative Catalog Number: BSS-IHC0670R-50
• Manufacturer: Bioss
• Category: Kits/Assays
• Species Reactivity: Rat
• Alternative Names: AU040756, DARPP-32, DARPP32, DARPP32 (phospho T75), p-DARPP32 (phospho T75), PPP1R1B(phospho T75), DARPP 32, Dopamine and cAMP regulated neuronal phosphoprotein, Dopamine and cAMP regulated phosphoprotein DARPP 32, Dopamine and cAMP regulated phosphoprotein DARPP32, FLJ20940, IPPD, Neuronal phosphoprotein DARPP 32, PPP1R1B, Protein phosphatase 1 regulatory (inhibitor) subunit 1B, Protein phosphatase 1 regulatory subunit 1B, PPR1B_HUMANa

Product Description

DARPP-32 is a dopamine (DA) and AMP-regugated ~32 kDa phosphoprotein that is associated with dopaminoceptive neurons. The protein inhibits Protein Phosphatase I when it is phosphorylated on Thr34. In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA. Phosphorylation of DARPP-32 is thought to play a critical role in the regugation of dopaminergic neurotransmission. In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac.

Product Properties

• Samples: FFPE tissue
• Target: Rat DARPP32

Images

IHC0670R