Synthetic peptide, corresponding to amino acids N-terminus of Human C/EBP-alpha.
Conjugation:
Unconjugated
Alternative Names:
CCAAT/enhancer-binding protein alpha, C/EBP alpha, CEBPA, C/EBP alpha, C/EBPalpha
C/EBP alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP alpha is a basic region/leucine zipper transcription factor selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP alpha uses a bipartite structural motif to bind DNA and appears to function exclusively in terminally differentiated, growtharrested cells. In the liver, C/EBP alpha is a transactivator of several genes, which are regulated by growth hormone. Growth hormone enhances not only the levels of C/EBP alpha mRNA and protein, but also the DNA-binding activity of C/EBP alpha. C/EBP alpha functions as an important transcription factor that regulates different genes, including Prolactin gene expression.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB 1:500 - 1:1000 IHC 1:50 - 1:100
Application Notes:
C/EBP-alpha (M15) polyclonal antibody detects endogenous levels of C/EBP-alpha protein.
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