Lamin A/C (R386) polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Lamin A/C (R386) polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS1446
• Supplier Catalog Number: BS1446
• Alternative Catalog Number: BWT-BS1446-50UL,BWT-BS1446-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 351-400 of Human Lamin A/C.
• Conjugation: Unconjugated
• Alternative Names: Prelamin-A/C, Lamin-A/C, Lamin A/C, LaminA/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1, Lamin A, LaminA, Lamin-A, Lamin C, LaminC, Lamin-C

Product Description

A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology.

Product Properties

• Molecular Weight: ~ 74, 65 kDa
• UniProt: P02545
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Application Notes

• Application Dilute: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
• Application Notes: Lamin A/C (R386) polyclonal antibody detects endogenous levels of Lamin A/C protein.