Caspase 9 (R192) polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Caspase 9 (R192) polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS1731
• Supplier Catalog Number: BS1731
• Alternative Catalog Number: BWT-BS1731-50UL,BWT-BS1731-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 280-320 of Human Caspase 9.
• Conjugation: Unconjugated
• Alternative Names: CASP 9, Caspase9, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6

Product Description

Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6.

Product Properties

• Molecular Weight: ~ 35,48 kDa
• UniProt: P55211
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Application Notes

• Application Dilute: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
• Application Notes: Caspase 9 (R192) polyclonal antibody detects endogenous levels of Caspase 9 protein.