Caper (R199) polyclonal antibody, Unconjugated, Rabbit

Catalog Number: BWT-BS1891
Article Name: Caper (R199) polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number: BWT-BS1891
Supplier Catalog Number: BS1891
Alternative Catalog Number: BWT-BS1891-50UL,BWT-BS1891-100UL
Manufacturer: Bioworld Technology
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic methylpeptide derived from human Histone H3 around the methylation site of Lysine 80.
Conjugation: Unconjugated
Alternative Names: Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ, Histone H3.2, Histone H3/m, Histone H3/o, HIST2H3A, HIST2H3C, H3F2, H3FM, HIST2H3D, Histone H3.3, 3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B, Histone H3.3C, Histone H3.5, H3F3C
Caper, also known as splicing factor HCC1 or hepatocellular carcinoma protein 1 and RNA binding region containing protein 2 (RNPC2), acts as a transcriptional coactivator for steroid nuclear receptors c-Jun, ERalpha and ERbeta. Caper, a nuclear protein with highest concentrations in nuclear speckles, plays a role in the pre-mRNA splicing process. Two isoforms of Caper, HCC1.3 and HCC1.4, co-localize with pre-mRNA splicing factor SC35 and uridine-rich small nuclear RNAs. Caper is a widely expressed protein with highest levels detected in skeletal muscle, lung, brain and pancreas.
Molecular Weight: ~ 39 kDa
UniProt: O75787
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute: WB: 1:500~1:1000
Application Notes: Caper (R199) pAb detects endogenous levels of Caper (R199) protein.