Aldolase A (T9) polyclonal antibody, Unconjugated, Rabbit

Catalog Number: BWT-BS1912
Article Name: Aldolase A (T9) polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number: BWT-BS1912
Supplier Catalog Number: BS1912
Alternative Catalog Number: BWT-BS1912-50UL,BWT-BS1912-100UL
Manufacturer: Bioworld Technology
Host: Rabbit
Category: Antikörper
Application: IF, IHC, WB
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to the N-terminus of Human Aldolase A.
Conjugation: Unconjugated
Alternative Names: Fructose-bisphosphate aldolase A, Lung cancer antigen NY-LU-1, Muscle-type aldolase, ALDOA, ALDA
Fructose 1,6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate. Fructose 1,6-bisphosphate aldolase exists as three forms: the muscle-specific Aldolase A, the liver-specific Aldolase B, and the brain-specific Aldolase C. Aldolase A, B and C arose from a common ancestral gene from which Aldolase B first diverged. Aldolase A is one of the most highly-conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon, and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase Cnegative Purkinje cells.
Molecular Weight: ~ 40 kDa
UniProt: P04075
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Application Notes: Aldolase A (T9) polyclonal antibody detects endogenous levels of Aldolase A protein.