HXK I (F67) polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number:
BWT-BS1947
Supplier Catalog Number:
BS1947
Alternative Catalog Number:
BWT-BS1947-50UL,BWT-BS1947-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide, corresponding to amino acids 30-80 of Human HXK I.
Conjugation:
Unconjugated
Alternative Names:
Hexokinase-1, Hexokinase 1, Brain form hexokinase, Hexokinase type I, HK I, HK1
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB: 1:500~1:1000 IHC: 1:50~1:200
Application Notes:
HXK I (F67) polyclonal antibody detects endogenous levels of HXK I protein.
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