Synthetic peptide, corresponding to amino acids 400-450 of Human Stat5a.
Conjugation:
Unconjugated
Alternative Names:
Signal transducer and activator of transcription 5A, STAT5A, STAT5
Stat 5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96% sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB: 1:500~1000 IHC: 1:50~1:200 IF: 1:50~1:200
Application Notes:
Stat5a (S420) polyclonal antibody detects endogenous levels of Stat5a protein.
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