Synthetic peptide, corresponding to amino acids 5-45 of Human GALK1.
Conjugation:
Unconjugated
Alternative Names:
Galactokinase, Galactose kinase, GALK1, GALK
Galactose kinase (GALK1), also often designated galactokinase, is important in the first step of the galactose metabolism pathway. GALK1, which belongs to the GHMP kinase family of proteins, is a crucial enzyme for galactose metabolism. Defects in the gene encoding for galactose kinase, GALK1, can cause galactosemia II, an autosomal recessive disorder characterized by congenital cataracts during infancy, often within the first two weeks of life. In the adult population it can cause presenile cataracts that are secondary to accumulation of galactitol in the lens of the eye.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB: 1:500~1:1000
Application Notes:
GALK1 (E15) polyclonal antibody detects endogenous levels of GALK1 protein.
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