Synthetic peptide, corresponding to amino acids 614-667 of Human BRD3.
Conjugation:
Unconjugated
Alternative Names:
Bromodomain-containing protein 3, RING3-like protein, BRD3, KIAA0043, RING3L
The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomaincontaining proteins are ubiquitously expressed.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB:1:500~1:1000 IHC: 1:50~1:200
Application Notes:
BRD3 (F645) polyclonal antibody detects endogenous levels of BRD3 protein.
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