CYP2C8/9/18/19 (M136) polyclonal antibody, Unconjugated, Rabbit
Catalog Number:
BWT-BS2195
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| Article Name: | CYP2C8/9/18/19 (M136) polyclonal antibody, Unconjugated, Rabbit |
| Biozol Catalog Number: | BWT-BS2195 |
| Supplier Catalog Number: | BS2195 |
| Alternative Catalog Number: | BWT-BS2195-50UL,BWT-BS2195-100UL |
| Manufacturer: | Bioworld Technology |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | IF, IHC |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide, corresponding to amino acids 100-150 of Human CYP2C8. |
| Conjugation: | Unconjugated |
| Alternative Names: | Cytochrome P450 2C9, (R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, CYPIIC9, Cytochrome P-450MP, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 PB-1, S-mephenytoin 4-hydroxylase, CYP2C9, CYP2C10, Cytochrome P450 2C8, CYPIIC8, Cytochrome P450 IIC2, Cytochrome P450 MP-12, Cytochrome P450 MP-20, Cytochrome P450 form 1, S-mephenytoin 4-hydroxylase, CYP2C8, Cytochrome P450 2C18, CYPIIC18, Cytochrome P450-6b/29c, CYP2C18, Cytochrome P450 2C19, (R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, CYPIIC17, CYPIIC19, Cytochrome P450-11A, Cytochrome P450-254C, Mephenytoin 4-hydroxylase, CYP2C19, |
| The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP2C (CYPIIC) subfamily comprises a group of constitutively expressed genes, some phenobarbital-induced genes, and several genes associated with sex-specific expression. Originally, at least 7 genes were assigned to the CYP2C subfamily, which maps to human 10q24.1-q24.3 and mouse chromosome 19. Humans contain fewer genes in this cluster than do mice or rats. Four genes are arranged in the following order and orientation along human chromosome 10: RBP4, CYP2C18, CYP2C19/CYP2C9, and CYP2C8. The previsously identified CYP2C10 is an artifact of CYP2C9 and not a distinct isoform. All of the CYP2C proteins localize to the endoplasmic reticulum. |
| Molecular Weight: | ~ 60 kDa |
| UniProt: | P33260 |
| Purity: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Form: | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
| Application Dilute: | IHC: 1:50~1:200 IF: 1:50~1:200 |
| Application Notes: | CYP2C8/9/18/19 (M136) polyclonal antibody detects endogenous levels of CYP2C8/9/18/19 protein. |
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