PFKFB1 (E442) polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: PFKFB1 (E442) polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS2259
• Supplier Catalog Number: BS2259
• Alternative Catalog Number: BWT-BS2259-50UL,BWT-BS2259-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 410-460 of Human PFKFB1.
• Conjugation: Unconjugated
• Alternative Names: PFK-2 liver, PFKFB1, PFRX, F6PK, 6PF-2-K/Fru-2, 6-P2ASE liver isozyme, 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1,

Product Description

PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose-2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose-2,6-bisphosphate, and contains fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).

Product Properties

• Molecular Weight: ~ 55 kDa
• UniProt: P16118
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Application Notes

• Application Dilute: WB: 1:500~1:1000 IHC: 1:50~1:200
• Application Notes: PFKFB1 (E442) polyclonal antibody detects endogenous levels of PFKFB1 protein.