TAF I p48 (R318) polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: TAF I p48 (R318) polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS2313
• Supplier Catalog Number: BS2313
• Alternative Catalog Number: BWT-BS2313-50UL,BWT-BS2313-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 280-336 of Human TAF I p48.
• Conjugation: Unconjugated
• Alternative Names: TATA box-binding protein-associated factor RNA polymerase I subunit A, RNA polymerase I-specific TBP-associated factor 48 kDa, TAFI48, TATA box-binding protein-associated factor 1A, TBP-associated factor 1A, Transcription factor SL1, Transcription initiation factor SL1/TIF-IB subunit A, TAF1A

Product Description

For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter. Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB. The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter and RNA polymerase-specific complexes.

Product Properties

• Molecular Weight: ~ 53 kDa
• UniProt: Q15573
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Application Notes

• Application Dilute: WB: 1:500~1:1000 IHC: 1:50~1:200
• Application Notes: TAF I p48 (R318) polyclonal antibody detects endogenous levels of TAF I p48 protein.