Synthetic peptide, corresponding to amino acids 332-380 of Human ZDHHC9.
Conjugation:
Unconjugated
Alternative Names:
Palmitoyltransferase ZDHHC9, Zinc finger DHHC domain-containing protein 9, DHHC-9, DHHC9, Zinc finger protein 379, Zinc finger protein 380, ZDHHC9, CXorf11, ZDHHC10, ZNF379, ZNF380, CGI-89, UNQ261/PRO298
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC9 (zinc finger, DHHC-type containing 9), also known as DHHC9, CGI-89, ZNF379 or CXorf11, is a 364 amino acid protein that localizes to the membrane of the endoplasmic reticulum and contains one DHHC-type zinc finger. Expressed at high levels in brain, lung, kidney, liver and skeletal muscle, ZDHHC9 exists in a complex with GOLGA7 and, via its DHHC domain, functions as a palmitoyltransferase that is specific for H-Ras and N-Ras. Mutations in the gene encoding ZDHHC9 are associated with X-linked mental retardation and colorectal cancer, the latter of which suggests a role in tumorigenesis.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB: 1:500~1:1000 IHC: 1:50~1:200
Application Notes:
ZDHHC9 (K364) polyclonal antibody detects endogenous levels of ZDHHC9 protein.
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