Synthetic peptide, corresponding to amino acids 172-215 of Human FoxO4.
Conjugation:
Unconjugated
Alternative Names:
Forkhead box protein O4, Fork head domain transcription factor AFX1, AFX, AFX1, MLLT7, FOXO4
FOX4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
IHC:1:50~1:200
Application Notes:
FoxO4 (P191) polyclonal antibody detects endogenous levels of FoxO4 protein.
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