Synthetic peptide, corresponding to amino acids 301-350 of Human Haptoglobin.
Conjugation:
Unconjugated
Alternative Names:
Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain, HP
Haptoglobin (Hp) is a blood plasma protein that functions to bind free Hemoglobin that has been released from erythrocytes, thereby inhibiting its oxidative activity. During this process, Haptoglobin sequesters the iron within Hemoglobin, preventing iron-utilizing bacteria from benefitting from hemolysis. This function suggests that Haptoglobin concentrations may increase in response to inflammation. The resulting Haptoglobin-Hemoglobin complex is then removed by the reticulo-endothelial system. Due to cleavage of a common precursor protein during protein synthesis, Haptoglobin consists of two alpha and two beta chains, connected by disulfide bridges.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
IHC: 1:50~1:200
Application Notes:
Haptoglobin (V328) polyclonal antibody detects endogenous levels of Haptoglobin protein.
* VAT and and shipping costs not included. Errors and price changes excepted
