Synthetic peptide, corresponding to amino acids 1150-1200 of Human NCAM-L1.
Conjugation:
Unconjugated
Alternative Names:
MIC 5, antigen identified by monoclonal antibody R1, MASA, CD 171, MIC5, N CAML1, SPG1, N CAM L1, HSAS, CD171, CD171 antigen, SPG 1, L1 cell adhesion molecule, HSAS1, HGNC:7086, NEURAL CELL ADHESION MOLECULE L1 PRECURSOR, S10, CAML1
The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Application Notes:
NCAM-L1 (R1177) polyclonal antibody detects endogenous levels of NCAM-L1 protein.
* VAT and and shipping costs not included. Errors and price changes excepted
