brPTB, MIBP, nPTB, Polypyrimidine tract binding protein 2, PTB like protein, PTBP 2Ptbp2, Splicing regulator,
RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
