Adiponectin receptor protein 1, Progestin and adipoQ receptor family member I , CGI-45, PAQR1, ADIPOR1,
Regulate fatty acid oxidation and the uptake of glucose by adiponectin. Each receptor activates a unique set of signaling molecules including AMPK, p38 MAPK and PPAR?. AdipoR1 has a high-affinity for globular adiponectin and low-affinity for full-length adiponectin, while AdipoR2 has an intermediate affinity for both forms.