E3 ubiquitin protein ligase NEDD4 like protein, KIAA0439, NEDD4 2, NEDD4 2c, Nedd4-2, NEDD4-2a, NEDD4b, NEDD4L, NEDL3, RSP5,
NEDD4 was originally identified as a gene that is highly expressed in the early mouse embryonic central nervous system. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
