ARH12, ARHA, H12, RHO12, RHOA, RHOB, RHOC, RHOH12, Small GTP binding protein RhoA, Transforming protein RhoA,
Act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins (GAPs), which catalyze the hydrolysis of GTP to GDP.
