c met related tyrosine kinase, CD136 antigen, Macrophage stimulating 1 receptor, MSP receptor, p185 RON, PTK 8 Stem cell derived tyrosine kinase, MST1R variant RON30, MST1R variant RON62,
Ron is initially synthesized in the cells as a single-chain, pro-Ron precursor that is cleaved into the two active chains. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages.
