MEKK3 Rabbit monoclonal antibody, Unconjugated

Product Overview

• Article Name: MEKK3 Rabbit monoclonal antibody, Unconjugated
• Biozol Catalog Number: BWT-BS40326
• Supplier Catalog Number: BS40326
• Alternative Catalog Number: BWT-BS40326-50UL,BWT-BS40326-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: FC, ICC, IHC, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human MEKK3
• Conjugation: Unconjugated
• Alternative Names: MAP/ERK kinase kinase 3, MAP3K3, MAPK/ERK kinase kinase 3, MAPKKK3, MEK kinase 3, MEKK 3, MEKK3, Mitogen activated protein kinase kinase kinase 3,

Product Description

MAP kinase kinase kinase (MEKK3 or MAP3K3) is a serine/threonine protein kinase that activates SAPK and ERK via phosphorylation and activation of their respective MAP kinase kinases, SEK and MEK1/2. MEKK3 also stimulates MEK5 via activation of ERK5/BMK1, which is at least partly regulated by a direct interaction between MEK5 and MEKK3 via p67phox-Bem1p (PB1) protein-protein interaction domains found in both proteins.

Product Properties

• Molecular Weight: 71kDa
• UniProt: Q99759
• Purity: Affinity-chromatography
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application Notes

• Application Dilute: WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20 FC 1:50
• Application Notes: MEKK3 Antibody detects endogenous levels of MEKK3