Cdc23/APC8 Rabbit monoclonal antibody, Unconjugated

Product Overview

• Article Name: Cdc23/APC8 Rabbit monoclonal antibody, Unconjugated
• Biozol Catalog Number: BWT-BS40347
• Supplier Catalog Number: BS40347
• Alternative Catalog Number: BWT-BS40347-50UL,BWT-BS40347-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: ICC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human Cdc23/APC8
• Conjugation: Unconjugated
• Alternative Names: CDC23, ANAPC8, APC8, Cell division cycle 23, CUT23, Cyclosome subunit 8,

Product Description

Anaphase-promoting complex subunit 8 (APC8, CDC23) is a component of the tetratricopeptide repeat (TPR) APC/C sub-complex that also includes APC3 (CDC27) and APC6 (CDC16). APC8 protein associates with APC3 and APC6 to facilitate recruitment of the APC/C coactivation subunits CDC20 and Cdh1/FZR1. Research studies suggest that APC8 protein is overexpressed in papillary thyroid cancer and acts as an important regulator of cell cycle progression and cell growth.

Product Properties

• Molecular Weight: 64kDa
• UniProt: Q9UJX2
• Purity: Affinity-chromatography
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application Notes

• Application Dilute: WB 1:500~1:2000 ICC/IF 1:50~1:100
• Application Notes: Cdc23/APC8 Antibody detects endogenous levels of total Cdc23/APC8