HSPA4, APG-2, APG2, Heat shock 70kD protein 4, Hsp70RY, HSPH2, Hsp70, HS24/P52, Heat shock 70kDa protein 4, Heat shock protein 110 kDa,
The heat shock protein HSPA4 (Apg-2, HSP70RY) is a member of the heat-shock protein 110 (Hsp 110) subfamily of Hsp70 heat-shock proteins. Apg-2 has chaperone ability similiar to Hsp110, and it plays a role under non-stress conditions. Apg-2 interacts with TJP1/ZO-1 and functions as a regulator of ZO-1-ZONAB signaling in epithelial cells in response to cellular stress.
