Rac1/2/3 Rabbit monoclonal antibody, Unconjugated

Product Overview

• Article Name: Rac1/2/3 Rabbit monoclonal antibody, Unconjugated
• Biozol Catalog Number: BWT-BS40497
• Supplier Catalog Number: BS40497
• Alternative Catalog Number: BWT-BS40497-50UL,BWT-BS40497-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human Rac1/2/3
• Conjugation: Unconjugated
• Alternative Names: Cell migration-inducing gene 5 protein, EN-7, GX, p21-Rac1, p21-Rac2, p21-Rac3, RAC1, RAC2, RAC3, TC25,

Product Description

In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development. GTP binding stimulates the activity of Rac/Cdc42, and the hydrolysis of GTP to GDP through the proteins intrinsic GTPase activity, rendering it inactive.

Product Properties

• Molecular Weight: 21kDa
• UniProt: P63000
• Purity: Affinity-chromatography
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application Notes

• Application Dilute: WB 1:500~1:2000
• Application Notes: Rac1/2/3 Antibody detects endogenous levels of total Rac1/2/3