A synthesized peptide derived from human REST / NRSF
Conjugation:
Unconjugated
Alternative Names:
NRSF, RE1 silencing transcription factor, Repressor binding to the X2 box, rest, X2 box repressor, XBR,
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes.