A synthesized peptide derived from human LIM Kinase 1
Conjugation:
Unconjugated
Alternative Names:
LIM kinase, LIMK 1, LIMK,
Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.