AURKA (phospho-T288) polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: AURKA (phospho-T288) polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS4260
• Supplier Catalog Number: BS4260
• Alternative Catalog Number: BWT-BS4260-50UL,BWT-BS4260-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic phosphopeptide derived from human AURKA around the phosphorylation site of Threonine 288.
• Conjugation: Unconjugated
• Alternative Names: Aurora kinase A, Aurora 2, Aurora/IPL1-related kinase 1, ARK-1, Aurora-related kinase 1, hARK1, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A, AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6

Product Description

Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.

Product Properties

• Molecular Weight: ~ 46 kDa
• UniProt: O14965
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Application Notes

• Application Dilute: IHC: 1:50~1:200
• Application Notes: p-AURKA (T288) polyclonal antibody detects endogenous levels of AURKA only when phosphorylated at Thr288.