Phospho-Cdc6 (Ser106) Recombinant Rabbit mAb, Unconjugated

Catalog Number: BWT-BS43087
Article Name: Phospho-Cdc6 (Ser106) Recombinant Rabbit mAb, Unconjugated
Biozol Catalog Number: BWT-BS43087
Supplier Catalog Number: BS43087
Alternative Catalog Number: BWT-BS43087-50UL,BWT-BS43087-100UL
Manufacturer: Bioworld Technology
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser106 of human Cdc6
Conjugation: Unconjugated
Alternative Names: CDC18L, HsCDC6, MGORS5, HsCDC18
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]
Molecular Weight: 63 kDa
UniProt: Q99741
Purity: Affinity Purification
Form: Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Application Dilute: WB: 1:1000
Application Notes: IgG