Phospho-ATR (Thr1989) Recombinant Rabbit mAb, Unconjugated

Catalog Number: BWT-BS43398
Article Name: Phospho-ATR (Thr1989) Recombinant Rabbit mAb, Unconjugated
Biozol Catalog Number: BWT-BS43398
Supplier Catalog Number: BS43398
Alternative Catalog Number: BWT-BS43398-50UL,BWT-BS43398-100UL
Manufacturer: Bioworld Technology
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr1989 of human ATR
Conjugation: Unconjugated
Alternative Names: FRP1, MEC1, SCKL, FCTCS, SCKL1
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
Molecular Weight: 301 kDa
UniProt: Q13535
Purity: Affinity Purification
Form: Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Application Dilute: WB: 1:1000
Application Notes: IgG