IL1 Receptor I Recombinant Rabbit mAb, Unconjugated
Biozol Catalog Number:
BWT-BS48443
Supplier Catalog Number:
BS48443
Alternative Catalog Number:
BWT-BS48443-50UL,BWT-BS48443-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Mouse
Immunogen:
Recombinant protein of mouse IL1 Receptor I
Conjugation:
Unconjugated
Alternative Names:
IL-iR, CD121a, CD121b, IL-1R1, Il1r-1
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (By similarity).
Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Application Dilute:
WB: 1:1000
Application Notes:
IgG
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