A synthetic peptide corresponding to residues in Human HEATR1.
Conjugation:
Unconjugated
Alternative Names:
HEAT repeat-containing protein 1, Protein BAP28, N-terminally processed, HEATR1, BAP28
HEATR1 (HEAT repeat containing 1), also known as BAP28, is a 2,144 amino acid nuclear protein involved in nucleolar processing of pre-18S ribosomal RNA. HEATR1 is a member of the HEATR1/UTP10 family and contains one HEAT repeat. The gene encoding HEATR1 is located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinsons disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB: 1:500~1:1000
Application Notes:
HEATR1 polyclonal antibody detects endogenous levels of HEATR1 protein.
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