A synthetic peptide corresponding to residues in Human CD101.
Conjugation:
Unconjugated
Alternative Names:
Immunoglobulin superfamily member 2, IgSF2, Cell surface glycoprotein V7, Glu-Trp-Ile EWI motif-containing protein 101, EWI-101, CD101, CD101, EWI101, IGSF2, V7
CD101 is a disulfide-linked homodimeric polypeptide. The gene encoding the CD101 antigen is identical to the gene encoding for the V7 antigen, which corresponds to a type I transmembrane protein containing seven Ig-like loops in its extracellular domain. CD101 may play an important regulatory role during T cell activation and may also be useful in combination with other markers for the diagnosis of LCH (Langerhans cell histiocytosis). CD101 is expressed on monocytes, granulocytes, dendritic cells and at low levels on a subset of peripheral T-cells comprising both CD4+ and CD8+, as well as both CD45RA+ and CD45RO+ cells. Expression of CD101 increases upon T cell activation.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB: 1:500~1:1000
Application Notes:
CD101 polyclonal antibody detects endogenous levels of CD101 protein.
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