Cyclin H polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number:
BWT-BS6099
Supplier Catalog Number:
BS6099
Alternative Catalog Number:
BWT-BS6099-50UL,BWT-BS6099-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
IP, WB
Species Reactivity:
Human
Immunogen:
Recombinant fusion protein of human Cyclin H(NP_001230.1).
Conjugation:
Unconjugated
Alternative Names:
CCNH,CAK,CycH,p34,p37,cyclin-H
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB,1:500 - 1:2000|IP,1:50 - 1:200
Application Notes:
Polyclonal Antibodies
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