RGPD1/2/3/4/5/8 polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: RGPD1/2/3/4/5/8 polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS62454
• Supplier Catalog Number: BS62454
• Alternative Catalog Number: BWT-BS62454-50UL,BWT-BS62454-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Rat
• Immunogen: Synthetic peptide, corresponding to Human RGPD1/2/3/4/5/8.
• Conjugation: Unconjugated
• Alternative Names: RANBP2-like and GRIP domain-containing protein 1, Ran-binding protein 2-like 6, RanBP2-like 6, RanBP2L6, RGPD1, RANBP2L6, RGP1, RANBP2-like and GRIP domain-containing protein 2, Ran-binding protein 2-like 2, RanBP2-like 2, RanBP2L2, RGPD2, RANBP2L2, RGP2, RanBP2-like and GRIP domain-containing protein 3, RGPD3, RGP3, RanBP2-like and GRIP domain-containing protein 4, RGPD4, RGP4, RANBP2-like and GRIP domain-containing protein 5/6, Ran-binding protein 2-like 1/2, RanBP2-like 1/2, RanBP2L1, RanBP2L2, Sperm membrane protein BS-63, RGPD5, RANBP2L1, RGP5, RGP7, RGPD7, RGPD6, RANBP2L2, RGP6, RANBP2-like and GRIP domain-containing protein 8, Ran-binding protein 2-like 3, RanBP2-like 3, RanBP2L3, RGPD8, RANBP2ALPHA, RANBP2L1, RANBP2L3

Product Description

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated protein (Cas9) system is an adaptive immune response defense mechanism used by archea and bacteria for the degradation of foreign genetic material. This mechanism can be repurposed for other functions, including genomic engineering for mammalian systems, such as gene knockout (KO) and gene activation. CRISPR Activation Plasmid products enable the identification and upregulation of specific genes by utilizing a D10A and N863A deactivated Cas9 (dCas9) nuclease fused to a VP64 activation domain, in conjunction with sgRNA (MS2), a target-specific sgRNA engineered to bind the MS2-P65-HSF1 fusion protein. This synergistic activation mediator (SAM) transcription activation system provides a robust system to maximize the activation of endogenous gene expression.

Product Properties

• Molecular Weight: ~ 198 kDa
• UniProt: P0DJD0
• Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Application Notes

• Application Dilute: WB:1:500~1:1000
• Application Notes: RGPD1/2/3/4/5/8 polyclonal antibody detects endogenous levels of RGPD1/2/3/4/5/8 protein.