Cyclophilin B(Loading Control) monoclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Cyclophilin B(Loading Control) monoclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS65514
• Supplier Catalog Number: BS65514
• Alternative Catalog Number: BWT-BS65514-50UL,BWT-BS65514-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant human Cyclophilin B:C terminus
• Conjugation: Unconjugated
• Alternative Names: Cphn 2, Cphn2, CyP 20b, CYP S1, CYP-S1, CYPB, MGC14109, MGC2224, peptidyl prolyl cis trans isomerase B, Peptidyl prolyl cis trans isomerase B precursor, Peptidyl-prolyl cis-trans isomerase B precursor, Peptidylprolyl isomerase B, PPIase, PPIB, Rotamase, S cyclophilin, SCYLP, PPIB_HUMAN.

Product Description

The cyclophilins are a conserved class of proteins that bind the immunosuppressive drug cyclosporin A (CsA) with high affinity. CsA blocks helper T-cell activation at a step between T-cell receptor stimulation and the transcriptional activation of cytokine genes. Cyclophilins from many species possess peptidyl-prolyl cis-trans isomerase (PPIase) activity that is blocked by CsA and therefore may be relevant in CsA-mediated immunosuppression.

Product Properties

• Molecular Weight: ~18kDa
• UniProt: P23284
• Purity: affinity purified by Protein A
• Form: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Application Notes

• Application Dilute: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
• Application Notes: Cyclophilin B monoclonal Antibody detects endogenous levels of Cyclophilin B protein.