TBCEL Polyclonal Antibody, Unconjugated, Rabbit

Catalog Number: BWT-BS65645
Article Name: TBCEL Polyclonal Antibody, Unconjugated, Rabbit
Biozol Catalog Number: BWT-BS65645
Supplier Catalog Number: BS65645
Alternative Catalog Number: BWT-BS65645-50UL,BWT-BS65645-100UL
Manufacturer: Bioworld Technology
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Mouse, Rat
Immunogen: KLH conjugated synthetic peptide derived from human TBCEL
Conjugation: Unconjugated
Alternative Names: EL, Leucine-rich repeat-containing protein 35, LRRC35, TBCEL, TBCEL_HUMAN, Tubulin folding cofactor E-like, Tubulin-specific chaperone cofactor E-like protein.
TBCEL is a 424 amino acid cytoplasmic protein that acts as a regulator of tubulin stability. While abundantly expressed in testis, TBCEL is also present in several tissues at a much lower level. TBCEL contains seven LRR (leucine-rich) repeats, one LRRCT domain and one ubiquitin-like domain. The gene that encodes TBCEL consists of 66,704 bases and maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11.
Molecular Weight: 48 kD
UniProt: Q5QJ74
Purity: affinity purified by Protein A
Form: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Application Dilute: WB=1:500-2000
Application Notes: TBCEL Polyclonal Antibody detects endogenous levels of TBCEL protein.