phospho-RACGAP1 (Ser387) Polyclonal Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: phospho-RACGAP1 (Ser387) Polyclonal Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS65993
• Supplier Catalog Number: BS65993
• Alternative Catalog Number: BWT-BS65993-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Bovine, Canine, Human, Mouse, Rat
• Immunogen: KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387:RI(p-S)GC
• Conjugation: Unconjugated
• Alternative Names: RACGAP1 (phospho S387), p-RACGAP1(S387), p-RACGAP1(Ser387), GAP, Gap1, GTPase activating protein, HsCYK 4, HsCYK4, ID GAP, KIAA1478, MgcRacGAP, Rac GTPase activating protein 1, RACGAP 1.

Product Description

Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

Product Properties

• Molecular Weight: 71kDa
• UniProt: Q9H0H5
• Purity: affinity purified by Protein A
• Form: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Application Notes

• Application Dilute: WB=1:500-2000
• Application Notes: phospho-RACGAP1 (Ser387) Polyclonal Antibody detects endogenous levels of RACGAP1 alpha protein only when phosphorylated at Ser387.