KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PLK1.
Conjugation:
Unconjugated
Alternative Names:
PLK1,PLK,STPK13
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis, hence, it is a target for cancer therapy.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB,1:500 - 1:1000|IHC,1:100 - 1:200
Application Notes:
PLK1 polyclonal antibody detects endogenous levels of PLK1 protein.
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