CHRDL1 polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: CHRDL1 polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS66188
• Supplier Catalog Number: BS66188
• Alternative Catalog Number: BWT-BS66188-50UL, BWT-BS66188-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IHC-P, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide of human CHRDL1
• Conjugation: Unconjugated
• Alternative Names: chordin-like 1, CHL, MGC1, MGCN, VOPT, NRLN1, dA141H5.1

Product Description

Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.

Product Properties

• Molecular Weight: ~ 52 kDa
• UniProt: Q9BU40
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Application Notes

• Application Dilute: WB: 1:500-1:1000 IHC-P: 1:50-1:100
• Application Notes: CHRDL1 polyclonal antibody detects endogenous levels of CHRDL1 protein.