Monoclonal Anti-MMAE specific Antibody, Rabbit IgG (M1D12), Unconjugated Preis auf Anfrage
Biozol Catalog Number:
BWT-BS66200
Supplier Catalog Number:
BS66200
Alternative Catalog Number:
BWT-BS66200-1UNIT
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
ELISA
Immunogen:
MMAE-BSA
Conjugation:
Unconjugated
Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several cancer types. Anti-MMAE antibody is a rabbit monoclonal antibody specially react with MMAE without MMAF, which is more sensitive than mouse antibody. The anti-MMAE antibody is a useful reagent in PK assay to determine conjugated antibodies.
Purity:
Protein A purified / Protein G purified
Form:
Lyophilized from 0.22 µm filtered solution in PBS, pH7.4 with trehalose as protectant.
Application Dilute:
ELISA 0.06-125 ng/mL
Application Notes:
Specifically recognizes MMAE and does not recognize MMAF.
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