HTRA3 polyclonal antibody, Unconjugated, Rabbit

Catalog Number: BWT-BS72466
Article Name: HTRA3 polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number: BWT-BS72466
Supplier Catalog Number: BS72466
Alternative Catalog Number: BWT-BS72466-50UL,BWT-BS72466-100UL
Manufacturer: Bioworld Technology
Host: Rabbit
Category: Antikörper
Application: IHC, WB
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human HTRA3(NP_444272.1).
Conjugation: Unconjugated
Alternative Names: HTRA3,Prsp,Tasp
Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.
Molecular Weight: 49KDa
UniProt: P83110
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute: WB,1:500 - 1:2000|IHC,1:50 - 1:200
Application Notes: Polyclonal Antibodies