CoA synthase (COASY) polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number:
BWT-BS74775
Supplier Catalog Number:
BS74775
Alternative Catalog Number:
BWT-BS74775-50UL,BWT-BS74775-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant fusion protein of human CoA synthase (COASY)(NP_079509.5).
Conjugation:
Unconjugated
Alternative Names:
COASY,DPCK,NBIA6,NBP,PPAT,UKR1,pOV-2
Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB,1:500 - 1:2000|IHC,1:100 - 1:200
Application Notes:
Unmodification
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